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H. Gracies - Y. Lachkar - J. Da Cunha - J. Kopel   Glaucoma Institute - Foundation Hospital Saint-Joseph, Paris - France

6^th Congress of the European Glaucoma Society - London - 29 juin 2000

Introduction Population Matériel et méthodes Résultats Discussion Conclusion Références

Purpose Population Materials and methods Results Discussion Conclusion References

Purpose: Selective laser trabeculoplasty (SLT) is a new technique developed to selectively target pigmented trabecular meshwork. We investigated the safety and efficacy of this technique to lower intraocular pressure (IOP).

Methods: Fifty nine eyes with uncontrolled open angle glaucoma (OAG) with prior medical therapy were treated with the Coherent Selecta 7000 ^TM (Coherent Inc., Palo Alto, CA), a frequency doubled Q switched Nd:Yag laser. Approximately 110 laser spots were applied over 360° of the trabecular meshwork. Efficacy was determined 5 weeks, 1 month, 3 months, 6 months and one year after the procedure.

Results: The average preoperative IOP was 25.05mmHg .Mean post operative IOP (at one year) was 15.76mmHg. Mean percentage reduction was 32.43% at 3 months after operation, 32.51% at six months and 33.51% at one year. Transient post operative pressure spike of 5mmHg or greater resolved in 24 hours was observed in 5 eyes.

Conclusion: SLT appears to be an effective and safe technique for lowering IOP and could be an alternative to Argon laser trabeculoplasty.

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H. Gracies , Y. Lachkar, J. Kopel, F. Kotobi, Ph.Demailly Institut du Glaucome, fondation-hôpital Saint-Joseph, Paris France

Comité de Lutte contre le Glaucome-VIII^e Symposium international - Paris -31 janvier 1998

Abstract

Table des matières

• Résultats cliniques de la trabéculoplastie au laser sélectif

• Objectifs

• Population

• Matériel et méthodes

• Résultats

• Résultats

• Discussion

• Photo1 : cellule du trabéculum in vitro au microscope électronique. Les grains de mélanine sont au sein des lysozomes (photo Latina et Park).

• Photo2 : cellule du trabéculum 4h après irradiation à forte dose par laser Nd:YAG à commutation de Q. Les membranes lysozomiales et les grains de mélanine sont brisés (photo Latina et Park).

• Conclusion

• Référence